Increased matriptase zymogen activation in inflammatory skin disorders

Matriptase, a type 2 transmembrane serine protease, and its inhibitor hepatocyte growth factor activator inhibitor (HAI)-1 are required for normal epidermal barrier function, and matriptase activity is tightly regulated during this process. We therefore hypothesized that this protease system might b...

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Detalhes bibliográficos
Main Authors: Chen, Cheng-Jueng, Wu, Bai-Yao, Tsao, Pai-In, Chen, Chi-Yung, Wu, Mei-Hsuan, Chan, Yee Lam E., Lee, Herng-Sheng, Johnson, Michael D., Eckert, Richard L., Chen, Ya-Wen, Chou, Fengpai, Wang, Jehng-Kang, Lin, Chen-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Extracellular Matrix, Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063967/
https://ncbi.nlm.nih.gov/pubmed/21123732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00403.2010
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