In vivo Endocrine Secretion of Prostacyclin Following Expression of a Cyclooxygenase-1/Prostacyclin Fusion Protein in the Salivary Glands of Rats Via Nonviral Gene Therapy

Pulmonary arterial hypertension (PAH) is a progressive disease that culminates in right heart failure and death. Prostacyclin (PGI2) and its derivatives are effective treatments for PAH when administered as continuous parenteral infusions. This treatment paradigm requires medical sophistication, and...

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Bibliografske podrobnosti
izdano v:Hum Gene Ther
Main Authors: Wang, Zhimin, Benza, Raymond L., Zourelias, Lee, Sanguino, Angela, Geguchadze, Ramaz, Shields, Kelly J., Wu, Changgong, Highland, Kristin B., Passineau, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567413/
https://ncbi.nlm.nih.gov/pubmed/28530128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.040
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