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EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines
Concurrent amplifications of EGFR and PDGFRA have been reported in up to 5% of glioblastoma (GBM) and it remains unclear why such independent amplification events, and associated receptor overexpression, would be adaptive during glioma evolution. Here, we document that EGFR and PDGFRA protein co-exp...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567352/ https://ncbi.nlm.nih.gov/pubmed/28831081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08940-9 |
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