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EGFR amplification and classical subtype are associated with a poor response to bevacizumab in recurrent glioblastoma

PURPOSE: The highly vascular malignant brain tumor glioblastoma (GBM) appears to be an ideal target for anti-angiogenic therapy; however, clinical trials to date suggest the VEGF antibody bevacizumab affects only progression-free survival. Here we analyze a group of patients with GBM who received be...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Hovinga, Koos E., McCrea, Heather J., Brennan, Cameron, Huse, Jason, Zheng, Junting, Esquenazi, Yoshua, Panageas, Katherine S., Tabar, Viviane
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752204/
https://ncbi.nlm.nih.gov/pubmed/30680510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-019-03102-5
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