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RhoE function is regulated by ROCK I-mediated phosphorylation
The Rho GTPase family member RhoE regulates actin filaments partly by binding to and inhibiting ROCK I, a serine/threonine kinase that induces actomyosin contractility. Here, we show that ROCK I can phosphorylate multiple residues on RhoE in vitro. In cells, ROCK I-phosphorylated RhoE localizes in t...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15775972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600612 |
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