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RhoE Inhibits Cell Cycle Progression and Ras-Induced Transformation
Rho GTPases are major regulators of cytoskeletal dynamics, but they also affect cell proliferation, transformation, and oncogenesis. RhoE, a member of the Rnd subfamily that does not detectably hydrolyze GTP, inhibits RhoA/ROCK signaling to promote actin stress fiber and focal adhesion disassembly....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515038/ https://ncbi.nlm.nih.gov/pubmed/15340047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7829-7840.2004 |
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