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RhoE function is regulated by ROCK I-mediated phosphorylation
The Rho GTPase family member RhoE regulates actin filaments partly by binding to and inhibiting ROCK I, a serine/threonine kinase that induces actomyosin contractility. Here, we show that ROCK I can phosphorylate multiple residues on RhoE in vitro. In cells, ROCK I-phosphorylated RhoE localizes in t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556412/ https://ncbi.nlm.nih.gov/pubmed/15775972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600612 |
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