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RhoE function is regulated by ROCK I-mediated phosphorylation

The Rho GTPase family member RhoE regulates actin filaments partly by binding to and inhibiting ROCK I, a serine/threonine kinase that induces actomyosin contractility. Here, we show that ROCK I can phosphorylate multiple residues on RhoE in vitro. In cells, ROCK I-phosphorylated RhoE localizes in t...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Riento, Kirsi, Totty, Nick, Villalonga, Priam, Garg, Ritu, Guasch, Rosa, Ridley, Anne J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2005
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556412/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15775972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600612
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