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RhoE function is regulated by ROCK I-mediated phosphorylation

The Rho GTPase family member RhoE regulates actin filaments partly by binding to and inhibiting ROCK I, a serine/threonine kinase that induces actomyosin contractility. Here, we show that ROCK I can phosphorylate multiple residues on RhoE in vitro. In cells, ROCK I-phosphorylated RhoE localizes in t...

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Hlavní autoři: Riento, Kirsi, Totty, Nick, Villalonga, Priam, Garg, Ritu, Guasch, Rosa, Ridley, Anne J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC556412/
https://ncbi.nlm.nih.gov/pubmed/15775972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600612
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