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RhoE Inhibits 4E-BP1 Phosphorylation and eIF4E Function Impairing Cap-dependent Translation

The Rho GTPase family member RhoE inhibits RhoA/ROCK signaling to promote actin stress fiber and focal adhesion disassembly. We have previously reported that RhoE also inhibits cell cycle progression and Ras-induced transformation, specifically preventing cyclin D1 translation. Here we investigate t...

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Bibliografiset tiedot
Päätekijät: Villalonga, Priam, de Mattos, Silvia Fernández, Ridley, Anne J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790958/
https://ncbi.nlm.nih.gov/pubmed/19850923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050120
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