4E-BP restrains eIF4E phosphorylation

In eukaryotes, mRNA translation is dependent on the cap-binding protein eIF4E. Through its simultaneous interaction with the mRNA cap structure and with the ribosome-associated eIF4G adaptor protein, eIF4E physically posits the ribosome at the 5′ extremity of capped mRNA. eIF4E activity is regulated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Translation (Austin)
Egile Nagusiak: Müller, David, Lasfargues, Charline, El Khawand, Sally, Alard, Amandine, Schneider, Robert J., Bousquet, Corinne, Pyronnet, Stéphane, Martineau, Yvan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2013
Gaiak:
Short Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718053/
https://ncbi.nlm.nih.gov/pubmed/26824022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trla.25819
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