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Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging
Telomeres are capping structures at the ends of eukaryotic chromosomes, which consist of repetitive DNA bound to an array of specialized proteins. Telomeres are part of the constitutive heterochromatin and are subjected to epigenetic modifications. The function of telomeres is to prevent chromosome...
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| Natura: | Artigo |
| Lingua: | Inglês |
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2005
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556402/ https://ncbi.nlm.nih.gov/pubmed/15775986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600598 |
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