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Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc(–/–) mice with short telomeres
Reconstitution of telomerase activity is proposed as a potential gene therapy to prevent, or rescue, age-related diseases produced by critical telomere shortening. However, it is not known whether or not short telomeres are irreversibly damaged. We addressed this by re-introducing telomerase in late...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084029/ https://ncbi.nlm.nih.gov/pubmed/11520856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve174 |
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