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Telomere Length Dynamics and Chromosomal Instability in Cells Derived from Telomerase Null Mice

To study the effect of continued telomere shortening on chromosome stability, we have analyzed the telomere length of two individual chromosomes (chromosomes 2 and 11) in fibroblasts derived from wild-type mice and from mice lacking the mouse telomerase RNA (mTER) gene using quantitative fluorescenc...

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Bibliographic Details
Main Authors: Hande, M. Prakash, Samper, Enrique, Lansdorp, Peter, Blasco, María A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132934/
https://ncbi.nlm.nih.gov/pubmed/10037783
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