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Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging

Telomeres are capping structures at the ends of eukaryotic chromosomes, which consist of repetitive DNA bound to an array of specialized proteins. Telomeres are part of the constitutive heterochromatin and are subjected to epigenetic modifications. The function of telomeres is to prevent chromosome...

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Detalhes bibliográficos
Autor principal: Blasco, María A
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556402/
https://ncbi.nlm.nih.gov/pubmed/15775986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600598
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