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Role of Telomeres and Telomerase in Aging and Cancer

Telomeres progressively shorten throughout life. A hallmark of advanced malignancies is the ability for continuous cell divisions that almost universally correlates with the stabilization of telomere length by the reactivation of telomerase. The repression of telomerase and shorter telomeres in huma...

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Bibliografiske detaljer
Udgivet i:Cancer Discov
Hovedforfatter: Shay, Jerry W.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893918/
https://ncbi.nlm.nih.gov/pubmed/27029895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0062
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