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Role of Telomeres and Telomerase in Aging and Cancer

Telomeres progressively shorten throughout life. A hallmark of advanced malignancies is the ability for continuous cell divisions that almost universally correlates with the stabilization of telomere length by the reactivation of telomerase. The repression of telomerase and shorter telomeres in huma...

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Publicat a:Cancer Discov
Autor principal: Shay, Jerry W.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893918/
https://ncbi.nlm.nih.gov/pubmed/27029895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0062
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