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Role of Telomeres and Telomerase in Aging and Cancer

Telomeres progressively shorten throughout life. A hallmark of advanced malignancies is the ability for continuous cell divisions that almost universally correlates with the stabilization of telomere length by the reactivation of telomerase. The repression of telomerase and shorter telomeres in huma...

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Bibliografiska uppgifter
I publikationen:Cancer Discov
Huvudupphovsman: Shay, Jerry W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893918/
https://ncbi.nlm.nih.gov/pubmed/27029895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0062
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