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Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases

Telomeres, the protective ends of linear chromosomes, shorten throughout an individual’s lifetime. Telomere shortening is a hallmark of molecular aging and is associated with premature appearance of diseases associated with aging. Here, we discuss the role of telomere shortening as a direct cause fo...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Bär, Christian, Blasco, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815611/
https://ncbi.nlm.nih.gov/pubmed/27081482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7020.1
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