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Structure of the WD40‐domain of human ATG16L1

Autophagy‐related protein ATG16L1 is a component of the mammalian ATG12∼ATG5/ATG16L1 complex, which acts as E3‐ligase to catalyze lipidation of LC3 during autophagosome biogenesis. The N‐terminal part of ATG16L1 comprises the ATG5‐binding site and coiled‐coil dimerization domain, both also present i...

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Publicat a:Protein Sci
Autors principals: Bajagic, Milica, Archna, Archna, Büsing, Petra, Scrima, Andrea
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563147/
https://ncbi.nlm.nih.gov/pubmed/28685931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3222
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