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Structure of the WD40‐domain of human ATG16L1
Autophagy‐related protein ATG16L1 is a component of the mammalian ATG12∼ATG5/ATG16L1 complex, which acts as E3‐ligase to catalyze lipidation of LC3 during autophagosome biogenesis. The N‐terminal part of ATG16L1 comprises the ATG5‐binding site and coiled‐coil dimerization domain, both also present i...
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| 發表在: | Protein Sci |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563147/ https://ncbi.nlm.nih.gov/pubmed/28685931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3222 |
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