Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

Prevention of inflammatory bowel disease (IBD) relies on tight control of inflammatory, cell death and autophagic mechanisms, but how these pathways are integrated at the molecular level is still unclear. Here we show that the anti-inflammatory protein A20 and the critical autophagic mediator Atg16l...

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Publicado en:Nat Commun
Main Authors: Slowicka, Karolina, Serramito-Gómez, Inmaculada, Boada-Romero, Emilio, Martens, Arne, Sze, Mozes, Petta, Ioanna, Vikkula, Hanna K., De Rycke, Riet, Parthoens, Eef, Lippens, Saskia, Savvides, Savvas N., Wullaert, Andy, Vereecke, Lars, Pimentel-Muiños, Felipe X., van Loo, Geert
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478926/
https://ncbi.nlm.nih.gov/pubmed/31015422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09667-z
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