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Identification, biochemical characterization and crystallization of the central region of human ATG16L1
ATG16L1 plays a major role in autophagy. It acts as a molecular scaffold which mediates protein–protein interactions essential for autophagosome formation. The ATG12~ATG5–ATG16L1 complex is one of the key complexes involved in autophagosome formation. Human ATG16L1 comprises 607 amino acids with thr...
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| Udgivet i: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5633923/ https://ncbi.nlm.nih.gov/pubmed/28994404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17013280 |
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