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Identification, biochemical characterization and crystallization of the central region of human ATG16L1

ATG16L1 plays a major role in autophagy. It acts as a molecular scaffold which mediates protein–protein interactions essential for autophagosome formation. The ATG12~ATG5–ATG16L1 complex is one of the key complexes involved in autophagosome formation. Human ATG16L1 comprises 607 amino acids with thr...

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Pubblicato in:Acta Crystallogr F Struct Biol Commun
Autori principali: Archna, Archna, Scrima, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5633923/
https://ncbi.nlm.nih.gov/pubmed/28994404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17013280
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