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Expression, purification and crystallization of the Atg5–Atg16 complex essential for autophagy
Atg5 is a novel 34 kDa protein that is covalently modified by Atg12, a ubiquitin-like modifier, and forms a complex with Atg16. The Atg12–Atg5–Atg16 complex localizes to autophagosome precursors and plays an essential role in autophagosome formation. Saccharomyces cerevisiae Atg5 in complex with the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2225175/ https://ncbi.nlm.nih.gov/pubmed/17012802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106036232 |
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