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Crystallization of the Atg12–Atg5 conjugate bound to Atg16 by the free-interface diffusion method
Autophagy mediates the bulk degradation of cytoplasmic components in lysosomes/vacuoles. Five autophagy-related (Atg) proteins are involved in a ubiquitin-like protein conjugation system. Atg12 is conjugated to its sole target, Atg5, by two enzymes, Atg7 and Atg10. The Atg12–Atg5 conjugates form a m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
International Union of Crystallography
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394807/ https://ncbi.nlm.nih.gov/pubmed/18421155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0909049507054799 |
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