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The Hsp40 J‐domain modulates Hsp70 conformation and ATPase activity with a semi‐elliptical spring

Regulatory protein interactions are commonly attributed to lock‐and‐key associations that bring interacting domains together. However, studies in some systems suggest that regulation is not achieved by binding interactions alone. We report our investigations on specific physical characteristics requ...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Bascos, Neil Andrew D., Mayer, Matthias P., Bukau, Bernd, Landry, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563141/
https://ncbi.nlm.nih.gov/pubmed/28685898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3223
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