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The Hsp40 J‐domain modulates Hsp70 conformation and ATPase activity with a semi‐elliptical spring

Regulatory protein interactions are commonly attributed to lock‐and‐key associations that bring interacting domains together. However, studies in some systems suggest that regulation is not achieved by binding interactions alone. We report our investigations on specific physical characteristics requ...

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Détails bibliographiques
Publié dans:Protein Sci
Auteurs principaux: Bascos, Neil Andrew D., Mayer, Matthias P., Bukau, Bernd, Landry, Samuel J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563141/
https://ncbi.nlm.nih.gov/pubmed/28685898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3223
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