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The Hsp40 J‐domain modulates Hsp70 conformation and ATPase activity with a semi‐elliptical spring

Regulatory protein interactions are commonly attributed to lock‐and‐key associations that bring interacting domains together. However, studies in some systems suggest that regulation is not achieved by binding interactions alone. We report our investigations on specific physical characteristics requ...

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Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Bascos, Neil Andrew D., Mayer, Matthias P., Bukau, Bernd, Landry, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563141/
https://ncbi.nlm.nih.gov/pubmed/28685898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3223
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