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Dose- and time-dependent α-synuclein aggregation induced by ferric iron in SK-N-SH cells
OBJECTIVE: Intracellular formation of Lewy body (LB) is one of the hallmarks of Parkinson’s disease. The main component of LB is aggregated α-synuclein, present in the substantia nigra where iron accumulation also occurs. The present study was aimed to study the relationship between iron and α-synuc...
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| Pubblicato in: | Neurosci Bull |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560295/ https://ncbi.nlm.nih.gov/pubmed/20502498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-1117-7 |
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