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The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity
Parkinson's disease (PD) is the most common motor disorder affecting the elderly. PD is characterized by the formation of Lewy bodies and death of dopaminergic neurons. The mechanisms underlying PD are unknown, but the discoveries that mutations in α-synuclein can cause familial PD and that α-s...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772599/ https://ncbi.nlm.nih.gov/pubmed/10934254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-16-06048.2000 |
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