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The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity
Parkinson's disease (PD) is the most common motor disorder affecting the elderly. PD is characterized by the formation of Lewy bodies and death of dopaminergic neurons. The mechanisms underlying PD are unknown, but the discoveries that mutations in α-synuclein can cause familial PD and that α-s...
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| Publicado en: | J Neurosci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772599/ https://ncbi.nlm.nih.gov/pubmed/10934254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-16-06048.2000 |
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