Sumoylation inhibits α-synuclein aggregation and toxicity

Posttranslational modification of proteins by attachment of small ubiquitin-related modifier (SUMO) contributes to numerous cellular phenomena. Sumoylation sometimes creates and abolishes binding interfaces, but increasing evidence points to another role for sumoylation in promoting the solubility o...

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Detalhes bibliográficos
Main Authors: Krumova, Petranka, Meulmeester, Erik, Garrido, Manuel, Tirard, Marilyn, Hsiao, He-Hsuan, Bossis, Guillaume, Urlaub, Henning, Zweckstetter, Markus, Kügler, Sebastian, Melchior, Frauke, Bähr, Mathias, Weishaupt, Jochen H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135405/
https://ncbi.nlm.nih.gov/pubmed/21746851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010117
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