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Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons
Fibrillar αSynuclein is the major constituent of Lewy bodies and Lewy neurites, the protein deposits characteristic for Parkinson’s disease (PD). Multiplications of the αSynuclein gene, as well as point mutations cause familial PD. However, the exact role of αSynuclein in neurodegeneration remains u...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3316935/ https://ncbi.nlm.nih.gov/pubmed/22167382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0926-8 |
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