Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro

Iron importer divalent metal transporter 1 (DMT1) plays a crucial role in the nigal iron accumulation in Parkinson’s disease (PD). Membrane hyperpolarization is one of the factors that could affect its iron transport function. Besides iron, selective activation of the ATP-sensitive potassium (K(ATP)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Du, Xixun, Xu, Huamin, Shi, Limin, Jiang, Zhifeng, Song, Ning, Jiang, Hong, Xie, Junxia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028757/
https://ncbi.nlm.nih.gov/pubmed/27646472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33674
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