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Screening of treatment targets for Alzheimer’s disease from the molecular mechanisms of impairment by β-amyloid aggregation and tau hyperphosphorylation

β-Amyloid (Aβ) over-expression and tau hyperphosphorylation are considered to be the central events in the pathogenesis of Alzheimer’s disease (AD). Studies on them may help elucidate the precise molecular pathogenesis of AD. Until now, although tau protein and Aβ remain the foci of AD research, the...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Lin, Lian-Feng, Luo, Huan-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560279/
https://ncbi.nlm.nih.gov/pubmed/21270904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-011-1040-6
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