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Alzheimer’s amyloid-β toxicity and tau hyperphosphorylation are linked via RCAN1

Amyloid-β peptide (Aβ) toxicity and tau hyperphosphorylation are hallmarks of Alzheimer’s disease (AD). How their molecular relationships may affect the etiology, progression, and severity of the disease, however, has not been elucidated. We now report that incubation of foetal rat cortical neurons...

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Detalhes bibliográficos
Main Authors: LLoret, A, Badia, MC, Giraldo, E, Ermak, G, Alonso, MD, Pallardó, FV, Davies, KJA, Viña, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690537/
https://ncbi.nlm.nih.gov/pubmed/21876249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110890
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