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Alzheimer’s amyloid-β toxicity and tau hyperphosphorylation are linked via RCAN1

Amyloid-β peptide (Aβ) toxicity and tau hyperphosphorylation are hallmarks of Alzheimer’s disease (AD). How their molecular relationships may affect the etiology, progression, and severity of the disease, however, has not been elucidated. We now report that incubation of foetal rat cortical neurons...

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Bibliographic Details
Main Authors: LLoret, A, Badia, MC, Giraldo, E, Ermak, G, Alonso, MD, Pallardó, FV, Davies, KJA, Viña, J
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690537/
https://ncbi.nlm.nih.gov/pubmed/21876249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110890
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