Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss

Characteristic features of Alzheimer’s disease are memory loss, plaques resulting from abnormal processing of amyloid precursor protein (APP), and presence of neurofibrillary tangles and dystrophic neurites containing hyperphosphorylated tau. Currently, it is not known what links these abnormalities...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Tiwari, Sachin Suresh, Mizuno, Keiko, Ghosh, Anshua, Aziz, Wajeeha, Troakes, Claire, Daoud, Jason, Golash, Vidushi, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035822/
https://ncbi.nlm.nih.gov/pubmed/27524794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww205
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