Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer’s disease

BACKGROUND: In Alzheimer’s disease synapse loss precedes neuronal loss and correlates best with impaired memory formation. However, the mechanisms underlying synaptic degeneration in Alzheimer’s disease are not well known. Further, it is unclear why synapses in AD cerebellum are protected from degen...

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Detaylı Bibliyografya
Yayımlandı:Mol Brain
Asıl Yazarlar: Tiwari, Sachin S, d’Orange, Marie, Troakes, Claire, Shurovi, Badrun N, Engmann, Olivia, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314762/
https://ncbi.nlm.nih.gov/pubmed/25631211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0096-z
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