Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss

Characteristic features of Alzheimer’s disease are memory loss, plaques resulting from abnormal processing of amyloid precursor protein (APP), and presence of neurofibrillary tangles and dystrophic neurites containing hyperphosphorylated tau. Currently, it is not known what links these abnormalities...

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Detalles Bibliográficos
Publicado en:Brain
Main Authors: Tiwari, Sachin Suresh, Mizuno, Keiko, Ghosh, Anshua, Aziz, Wajeeha, Troakes, Claire, Daoud, Jason, Golash, Vidushi, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl Peter
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035822/
https://ncbi.nlm.nih.gov/pubmed/27524794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aww205
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