Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease

This study was designed to test the interaction between amyloid-β and tau proteins as a determinant of metabolic decline in preclinical Alzheimer's disease (AD). We assessed 120 cognitively normal individuals with [(18)F]florbetapir positron emission tomography (PET) and cerebrospinal fluid (CS...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Pascoal, T A, Mathotaarachchi, S, Mohades, S, Benedet, A L, Chung, C-O, Shin, M, Wang, S, Beaudry, T, Kang, M S, Soucy, J-P, Labbe, A, Gauthier, S, Rosa-Neto, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262471/
https://ncbi.nlm.nih.gov/pubmed/27021814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.37
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