Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals

INTRODUCTION: Neurofilament light chain (NfL) is a promising blood biomarker to detect neurodegeneration in Alzheimer's disease (AD) and other brain disorders. However, there are limited reports of how longitudinal NfL relates to imaging biomarkers. We herein investigated the relationship betwe...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Benedet, Andréa L., Ashton, Nicholas J., Pascoal, Tharick A., Leuzy, Antoine, Mathotaarachchi, Sulantha, Kang, Min S., Therriault, Joseph, Savard, Melissa, Chamoun, Mira, Schöll, Michael, Zimmer, Eduardo R., Gauthier, Serge, Labbe, Aurélie, Zetterberg, Henrik, Blennow, Kaj, Neto, Pedro R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Special Section: Blood-Based Biomarkers for Alzheimer's Disease & Related Dementias. (Editor: Henrik Zetterberg)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816316/
https://ncbi.nlm.nih.gov/pubmed/31673598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.08.002
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