Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals

INTRODUCTION: Neurofilament light chain (NfL) is a promising blood biomarker to detect neurodegeneration in Alzheimer's disease (AD) and other brain disorders. However, there are limited reports of how longitudinal NfL relates to imaging biomarkers. We herein investigated the relationship betwe...

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Dettagli Bibliografici
Pubblicato in:Alzheimers Dement (Amst)
Autori principali: Benedet, Andréa L., Ashton, Nicholas J., Pascoal, Tharick A., Leuzy, Antoine, Mathotaarachchi, Sulantha, Kang, Min S., Therriault, Joseph, Savard, Melissa, Chamoun, Mira, Schöll, Michael, Zimmer, Eduardo R., Gauthier, Serge, Labbe, Aurélie, Zetterberg, Henrik, Blennow, Kaj, Neto, Pedro R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Special Section: Blood-Based Biomarkers for Alzheimer's Disease & Related Dementias. (Editor: Henrik Zetterberg)
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816316/
https://ncbi.nlm.nih.gov/pubmed/31673598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.08.002
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