Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals

INTRODUCTION: Neurofilament light chain (NfL) is a promising blood biomarker to detect neurodegeneration in Alzheimer's disease (AD) and other brain disorders. However, there are limited reports of how longitudinal NfL relates to imaging biomarkers. We herein investigated the relationship betwe...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Benedet, Andréa L., Ashton, Nicholas J., Pascoal, Tharick A., Leuzy, Antoine, Mathotaarachchi, Sulantha, Kang, Min S., Therriault, Joseph, Savard, Melissa, Chamoun, Mira, Schöll, Michael, Zimmer, Eduardo R., Gauthier, Serge, Labbe, Aurélie, Zetterberg, Henrik, Blennow, Kaj, Neto, Pedro R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Special Section: Blood-Based Biomarkers for Alzheimer's Disease & Related Dementias. (Editor: Henrik Zetterberg)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816316/
https://ncbi.nlm.nih.gov/pubmed/31673598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.08.002
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