Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid-positive individuals

INTRODUCTION: Neurofilament light chain (NfL) is a promising blood biomarker to detect neurodegeneration in Alzheimer's disease (AD) and other brain disorders. However, there are limited reports of how longitudinal NfL relates to imaging biomarkers. We herein investigated the relationship betwe...

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Veröffentlicht in:Alzheimers Dement (Amst)
Hauptverfasser: Benedet, Andréa L., Ashton, Nicholas J., Pascoal, Tharick A., Leuzy, Antoine, Mathotaarachchi, Sulantha, Kang, Min S., Therriault, Joseph, Savard, Melissa, Chamoun, Mira, Schöll, Michael, Zimmer, Eduardo R., Gauthier, Serge, Labbe, Aurélie, Zetterberg, Henrik, Blennow, Kaj, Neto, Pedro R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Special Section: Blood-Based Biomarkers for Alzheimer's Disease & Related Dementias. (Editor: Henrik Zetterberg)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816316/
https://ncbi.nlm.nih.gov/pubmed/31673598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.08.002
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