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Tau aggregation and its interplay with amyloid-β
Neurofibrillary tangles and amyloid plaques constitute the hallmark brain lesions of Alzheimer’s disease (AD) patients. Tangles are composed of fibrillar aggregates of the microtubule-associated protein tau, and plaques comprise fibrillar forms of a proteolytic cleavage product, amyloid-β (Aβ). Alth...
Gespeichert in:
| Veröffentlicht in: | Acta Neuropathol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4305093/ https://ncbi.nlm.nih.gov/pubmed/25492702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1371-2 |
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