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Are you TORCing tau me? Amyloid‐β blocks the conversation between lysosomes and mitochondria

How amyloid‐β (Aβ) and tau exacerbate Alzheimer's disease (AD) at a subcellular level is only incompletely understood. Norambuena et al (2018) report crosstalk between mitochondria and lysosomes and identify a role for lysosomal mTORC1 in the nutrient‐induced activation of mitochondria. This ly...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Polanco, Juan Carlos, Götz, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236328/
https://ncbi.nlm.nih.gov/pubmed/30389662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100839
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