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Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
BACKGROUND: The interferon (IFN)-induced, dsRNA-dependent serine/threonine protein kinase, PKR, plays a key regulatory role in the IFN-mediated anti-viral response by blocking translation in the infected cell by phosphorylating the alpha subunit of elongation factor 2 (eIF2). The human immunodeficie...
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| Publicado no: | Virol J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15737233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1743-422X-2-17 |
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