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An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription
Potent and selective recognition and modulation of disease-relevant RNAs remains a daunting challenge. We previously examined the utility of the U1A N-terminal RNA recognition motif as a scaffold for tailoring new RNA hairpin recognition, and showed that as few as one or two mutations can result in...
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| Udgivet i: | ACS Chem Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5199234/ https://ncbi.nlm.nih.gov/pubmed/27253715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00145 |
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