An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription

Potent and selective recognition and modulation of disease-relevant RNAs remains a daunting challenge. We previously examined the utility of the U1A N-terminal RNA recognition motif as a scaffold for tailoring new RNA hairpin recognition, and showed that as few as one or two mutations can result in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:ACS Chem Biol
Huvudupphovsmän: Crawford, David W., Blakeley, Brett D., Chen, Po-Han, Sherpa, Chringma, Le Grice, Stuart F.J., Laird-Offringa, Ite A., McNaughton, Brian R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199234/
https://ncbi.nlm.nih.gov/pubmed/27253715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00145
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk