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HMGA1 directly interacts with TAR to modulate basal and Tat-dependent HIV transcription

The transactivating response element (TAR) of human immunodeficiency virus 1 (HIV-1) is essential for promoter transactivation by the viral transactivator of transcription (Tat). The Tat-TAR interaction thereby recruits active positive transcription elongation factor b (P-TEFb) from its inactive, 7S...

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Autori principali: Eilebrecht, Sebastian, Wilhelm, Emmanuelle, Benecke, Bernd-Joachim, Bell, Brendan, Benecke, Arndt G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672287/
https://ncbi.nlm.nih.gov/pubmed/23392246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23686
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