The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion

Several age-related neurodegenerative disorders are associated with protein misfolding and aggregation of toxic peptides. α-synuclein (α-syn) aggregation and the resulting cytotoxicity is a hallmark of Parkinson's disease (PD) as well as dementia with Lewy bodies. Rising evidence points to olig...

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Dettagli Bibliografici
Pubblicato in:Aging (Albany NY)
Autori principali: von Einem, Bjoern, Eschbach, Judith, Kiechle, Martin, Wahler, Anke, Thal, Dietmar R., McLean, Pamela J., Weishaupt, Jochen H., Ludolph, Albert C., von Arnim, Christine A.F., Danzer, Karin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559169/
https://ncbi.nlm.nih.gov/pubmed/28722658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101261
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