α-synuclein interacts with SOD1 and promotes its oligomerization

BACKGROUND: Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) are both neurodegenerative diseases leading to impaired execution of movement. α-Synuclein plays a central role in the pathogenesis of PD whereas Cu, Zn superoxide dismutase (SOD1) is a key player in a subset of familial AL...

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Bibliographic Details
Published in:Mol Neurodegener
Main Authors: Helferich, Anika M., Ruf, Wolfgang P., Grozdanov, Veselin, Freischmidt, Axel, Feiler, Marisa S., Zondler, Lisa, Ludolph, Albert C., McLean, Pamela J., Weishaupt, Jochen H., Danzer, Karin M.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672499/
https://ncbi.nlm.nih.gov/pubmed/26643113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0062-3
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