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Drug Targets from Genetics: Alpha-Synuclein

One of the critical issues in Parkinson disease (PD) research is the identity of the specific toxic, pathogenic moiety. In PD, mutations in alpha-synuclein (αsyn) or multiplication of the SNCA gene encoding αsyn, result in a phenotype of cellular inclusions, cell death, and brain dysfunction. While...

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Autors principals: Danzer, Karin M., McLean, Pamela J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364517/
https://ncbi.nlm.nih.gov/pubmed/21838671
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