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Targeted Overexpression of Human Alpha-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
Microglial activation and adaptive immunity have been implicated in the neurodegenerative processes in Parkinson disease. It has been proposed that these responses may be triggered by modified forms of α-synuclein (αSYN), particularly nitrated species, which are released as a consequence of dopamine...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753200/ https://ncbi.nlm.nih.gov/pubmed/19018246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31818e5e99 |
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